WP 9 Long term effects of perinatal exposures to indoor allergens and microbes in respiratory and immunological health in children
Participating partners: THL, UU, CREAL, HMGU
In order to assess in a longitudinal direction the role of indoor pollution, this WP is nested in on-going studies that already have collected rich epidemiological data on immunological function, asthma and allergy based on several repeated exams along infancy and childhood. This WP builds on four birth cohorts (LUKAS, Finland; PIAMA, The Netherlands; LISA, Germany; INMA, Spain), that have collected house dust early in life and have been following the children for respiratory, immunological and inflammatory conditions. Outcome measurements are repeatedly measured at the age of 9-11 years, except LUKAS cohort, which will do the follow-up examination at the age of 6.5 years.
The work package aims to assess the long-term effects of indoor microbial and chemical exposures during early life a) on respiratory, inflammatory, and allergic health parameters at the age of 9-11 and b) on development of immune function up to age 6.5 years.
Further, the interconnection between chemical exposures, especially cleaning products, and the levels and characteristics of indoor microbial exposures will be assessed.
In order to assess in a longitudinal direction the role of indoor pollution, this WP is nested in on-going studies that already have collected rich epidemiological data on immunological function, asthma and allergy based on several repeated exams along infancy and childhood. This WP builds on four birth cohorts (LUKAS, Finland; PIAMA, The Netherlands; LISA, Germany; INMA, Spain), that have collected house dust early in life and have been following the children for respiratory, immunological and inflammatory conditions. Outcome measurements are repeatedly measured at the age of 9-11 years, except LUKAS cohort, which will do the follow-up examination at the age of 6.5 years.
The work package aims to assess the long-term effects of indoor microbial and chemical exposures during early life a) on respiratory, inflammatory, and allergic health parameters at the age of 9-11 and b) on development of immune function up to age 6.5 years.
Further, the interconnection between chemical exposures, especially cleaning products, and the levels and characteristics of indoor microbial exposures will be assessed.